Notes in Cell Communication & Cell Signaling

Unit 4- Cell Communication & Cell Signaling

Topics

  1. Host parasite interaction
    1. Recognition and entry processes of different pathogens like bacteria, viruses into animal and plant host cells
    2. Alteration of host cell behavior by pathogens
    3. Virus-induced cell transformation
    4. Pathogen-induced diseases in animals and plants
    5. Cell-cell fusion in both normal and abnormal cells
  2. Cell signalling
    1. Hormones and their receptors
    2. Cell surface receptor
    3. Signaling through G-protein coupled receptors
    4. Signal transduction pathways
    5. Second messengers
    6. Regulation of signaling pathways
    7. Bacterial and plant two-component signaling systems
    8. Bacterial chemotaxis
    9. Quorum sensing
  3. Cellular communication
    1. Regulation of hematopoiesis
    2. General principles of cell communication
    3. Cell adhesion and roles of different adhesion molecules
    4. Gap junctions
    5. Extracellular matrix
    6. Integrins
    7. Neurotransmission and its regulation.
  4. Cancer
    1. Genetic rearrangements in progenitor cells
    2. Oncogenes
    3. Tumor suppressor genes
    4. Cancer and the cell cycle
    5. Virus-induced cancer
    6. Metastasis
    7. Interaction of cancer cells with normal cells
    8. Apoptosis
    9. Therapeutic interventions of uncontrolled cell growth
  5. Innate and adaptive immune system
    1. Cells and molecules involved in innate and adaptive immunity
    2. Antigens, antigenicity and immunogenicity
    3. B and T cell epitopes
    4. Structure and function of antibody molecules
    5. Generation of antibody diversity
    6. Monoclonal antibodies
    7. Antibody engineering
    8. Antigen-antibody interactions
    9. MHC molecules
    10. Antigen processing and presentation
    11. Activation and differentiation of B and T cells
    12. B and T cell receptors
    13. Humoral and cell-mediated immune responses
    14. Primary and secondary immune modulation
    15. The complement system
    16. Toll-like receptors
    17. Cell-mediated effector functions
    18. Inflammation
    19. Hypersensitivity and autoimmunity
    20. Immune response during
      1. Bacterial (tuberculosis)
      2. Parasitic (malaria)
      3. Viral (HIV) infections
      4. Congenital and acquired immunodeficiencies
    21. Vaccines